DR. ALEX CARTER, Ph.D

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Post-Orgasmic Illness Syndrome (POIS)

Post-Orgasmic Illness Syndrome (POIS) is a rare and poorly understood condition that causes debilitating physical and cognitive symptoms following orgasm. Many individuals suffering from POIS feel isolated due to the lack of awareness and medical recognition. Below are 25 real-life experiences from individuals with POIS, describing their struggles and how they cope.

OUR STORY

"After orgasm, I feel like I’ve lost 50 IQ points. It’s like my brain shuts down, and I can’t focus or remember things. It affects my work, my relationships, and my confidence. I’ve found that antihistamines help a bit, but it’s still a daily battle."

James, 32

The Brain Fog Struggle

"After sex or even masturbation, I feel like I have the flu—fever, chills, muscle aches, exhaustion. It lasts for days. Doctors kept dismissing me until I found an online forum discussing POIS. Now, I take niacin before orgasm, and it's improved my symptoms significantly."

Alex, 28

The Flu-Like Symptoms

"POIS makes me feel like a different person. I become irritable, anxious, and depressed. I can’t socialize or function normally. I’ve learned to schedule intimacy around my work and responsibilities, but it’s frustrating to live this way."

David, 40

-Social Anxiety and Emotional Turmoil

"I’ve avoided relationships for years because of POIS. The idea of explaining this condition to a partner is terrifying. I tried dating, but the symptoms made me so withdrawn and exhausted that I had to end things."

Mark, 35

-Avoiding Relationships

"I’ve experimented with everything—magnesium, B vitamins, antihistamines, niacin. Some things help, some don’t. It’s frustrating that doctors don’t have answers, but I’ve found a combination that reduces my symptoms by 50%."

Ryan, 24

-Trial and Error with Supplements

"For decades, I thought I was just weak or had an immune disorder. Doctors tested me for everything—autoimmune diseases, chronic fatigue, allergies. It wasn’t until I found an online support group that I realized what I had."

John, 50

-Years of Misdiagnosis

"Doctors told me it was ‘all in my head.’ One even suggested I see a psychiatrist. I had to fight to be taken seriously. Now, I’m working with a specialist who at least acknowledges POIS exists."

Mike, 29

-The Frustration of Being Dismissed

"I love my girlfriend, but I’m scared of sex because I know what follows. She’s supportive, but it’s hard to explain why I sometimes need days to recover. I wish there were more awareness and research."

Daniel, 33

-The Fear of Intimacy

"I’ve noticed that certain foods and stress make POIS worse. Cutting out dairy and processed foods has helped. It’s not a cure, but it makes a difference."

Tom, 45

-Learning to Manage Triggers

"I can’t function at work for at least two days after orgasm. I’ve had to limit my sex life just to keep my job. It’s a terrible trade-off."

Steve, 38

-The Work Struggles

"I’ve joined POIS research studies, hoping for a cure. Knowing that researchers are finally taking this seriously gives me hope."

Chris, 31

-Finding Hope in Research

"No one understands what I go through. I can’t talk about this with friends or family without feeling embarrassed. Online forums have been my only support system."

Adam, 27

-The Isolation

"My wife is amazing, but POIS has put a strain on our marriage. She wants intimacy, but I have to plan everything carefully to avoid bad flare-ups."

Ben, 36

-Relationship Struggles

"After orgasm, my sleep is terrible. I wake up multiple times, have vivid nightmares, and feel unrested. I’ve started taking magnesium and melatonin, which helps slightly."

Kevin, 30

-Sleep Disruptions

"I noticed symptoms as a teenager but thought it was normal. Now, I realize it’s not, and I worry about how it will affect my future relationships."

Jake, 22

-Discovering POIS Young

"I’ve stopped searching for a miracle cure and focused on managing symptoms. Stress reduction, a healthy diet, and avoiding frequent orgasms have helped."

Will, 41

-Learning to Accept It

"I saw a doctor who suggested allergy treatments. It’s too early to tell if it’s working, but I’m willing to try anything."

Nathan, 34

-Trying Immunotherapy

"To the outside world, I’m successful and happy. Inside, I’m constantly dealing with POIS. It’s exhausting to hide it."

Peter, 48

-Living a Double Life

"I also have autoimmune issues, and I suspect POIS is connected. More research is needed, but I’m convinced there’s an immune system component to this."

Jason, 26

-The Link to Autoimmune Issues

"Even some doctors have never heard of POIS. It’s ridiculous that in 2024, so many suffer in silence because of ignorance."

Alan, 37

The Frustrating Lack of Awareness

"Going keto has actually helped my POIS symptoms. It’s not a cure, but reducing carbs has made my flare-ups less severe."

Sam, 34

-Trying Immunotherapy

"The depression and anxiety after orgasm are unbearable at times. Therapy has helped me cope emotionally, but the physical symptoms remain."

Oliver, 32

-The Impact on Mental Health

"The POIS forums have been a lifesaver. Knowing I’m not alone has been the biggest relief."

Henry, 39

-Finding Support in Online Communities

"I had to time my orgasms around my classes. If I had sex the night before an exam, I knew I’d fail. It’s a ridiculous way to live."

Patrick, 25

-Struggling in College

"I dream of the day when POIS is well understood and treatable. Until then, I just manage as best as I can."

Liam, 43

-Hoping for a Cure

These stories highlight the struggles, frustrations, and coping mechanisms of those living with POIS. The condition remains under-researched, but as awareness grows, so does the hope for better treatments and understanding. If you suffer from POIS, you are not alone. There are online communities and researchers working toward solutions.

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The POIS Community is a private, peer-led support space for those experiencing Post Orgasmic Illness Syndrome (POIS). We offer peer support, supplement strategies, and a space to connect and recover.
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